Publications

Books

CDs

Featured in Books

  • The Three Pound Universe. The Brain–From the Chemistry of the Mind to the New Frontier of the Soul, Judith Hooper and Dick Teresi, MacMillan,1986.
  • Apprentice to Genius. The Making of a Scientific Dynasty, Robert Kanigel, MacMillan, 1986.
  • Molecules of the Mind, John Franklin, Dell, 1987.
  • Anatomy of a Scientific Discovery, Jeff Goldberg, Bantam Books, 1988
  • Brain Storming, Solomon Snyder, Harvard University Press, 1989.
  • Pert, Candace. The Chemical Communicators. In: Healing and the Mind, Bill Moyers, Flowers, B.S. and Grubin, D. (Eds.). Doubleday & Co., New York, 1993, pp.177-193.
  • Pert, Candace. Molecules of Emotion: Why you feel the way you feel. Scribner, New York, 1997

Scientific Publications

1. Young, A.B., Pert, C.B., Brown, D.G., Taylor, K.M. and Snyder, S.H. Nuclear localization of histamine in neonatal rat brain. Science 173: 247-249, 1971.

2. Chou, T-C.T., Bennett, J.L., Pert, C.B. and Bueding, E. Effect of hycanthone and of two of its structural analogs on levels of uptake of 5-hydroxytryptamine in Schistosoma mansoni. J. Pharmacol. Exp. Ther. 186: 408-415, 1973.

3. Pert, C.B. and Snyder, S.H. Opiate receptor: demonstration in nervous tissue. Science 179: 1011-1014, 1973.

4. Pert, C.B. and Snyder, S.H. Properties of opiate-receptor binding in rat brain. Proc. Natl. Acad. Sci. USA 70: 2243-2247, 1973.

5. Kuhar, M.J., Pert, C.B. and Snyder, S.H. Regional distribution of opiate receptor binding in monkey and human brain. Nature 245: 447-450, 1973.

6. Pert, C.B., Pasternak, G. and Snyder, S.H. Opiate agonists and antagonists discriminated by receptor binding in brain. Science 182: 1359-1361, 1973.

7. Snyder, S.H., Yamamura, H.I., Pert, C.B., Logan, W.J. and Bennett, J.P. Neuronal uptake of neurotransmitters and their precursors: studies with “transmitter” amino acids and choline. In: New Concepts in Neurotransmitter Regulation, Mandell, A.J. (Ed.). Plenum Press, New York, 1973, pp. 195-222.

8. Pert, C.B. and Snyder, S.H. High affinity transport of choline into the myenteric plexus of guinea-pig intestine. J. Pharmacol. Exp. Ther. 191: 102-108, 1974.

9. Pert, C.B., Snowman, A.M. and Snyder, S.H. Localization of opiate receptor binding in synaptic membranes of rat brain. Brain Res. 70: 184-188, 1974.

10. Pert, C.B., Aposhian, D. and Snyder, S.H. Phylogenetic distribution of opiate receptor binding. Brain Res. 75: 356-361, 1974.

11. Snyder, S.H., Pert, C.B. and Pasternak, G.W. The opiate receptor. Annals of Int. Med. 81: 534-540, 1974.

12. Pert, C.B. and Snyder, S.H. Opiate receptor binding of agonists and antagonists affected differentially by sodium. Mol. Pharmacol. 10: 868-879, 1974.

13. Snyder, S.H., Pert, C.B. and Pasternak, G. Opiate receptor dynamics. In: Neuropsychopharmacology, Proceedings of the IX Congress of the Collegium Internationale Neuropsychopharmacologicum. Excerpta medica, Amsterdam, 1974, pp. 307-313.

14. Wilson, R.S., Rogers, M.E. Pert, C.B. and Snyder, S.H. Homologous N-alkylonorketobemidones. Correlation of receptor binding with analgesic potency. J. Med. Chem. 18: 240-242, 1975.

15. Pert, C.B. and Snyder, S.H. Differential interactions of agonists and antagonists with the opiate receptor. Neurosci. Res. Prog. Bull. 13: 73-79, 1975.

16. Pert, C.B. and Snyder, S.H. Identification of opiate receptor binding in intact animals. Life Sci. 16: 1623-1634, 1975.

17. Pert, C.B., Kuhar, M.J. and Snyder, S.H. Autoradiographic localization of the opiate receptor in rat brain. Life Sci. 16: 1849-1854, 1975.

18. Creese, I., Pasternak, G.W., Pert, C.B. and Snyder, S.H. Discrimination by temperature of opiate agonist and antagonist receptor binding. Life Sci. 16: 1837-1842, 1975.

19. Snyder, S.H., Pasternak, G.W. and Pert, C.B.. Opiate receptor mechanisms. In: Handbook of Psychopharmacology, Vol. 5, Synaptic Modulators. Plenum Press, New York, 1975, pp. 329-360.

20. Pert, C.B., Snyder, S.H. and May, E.L. Opiate receptor interactions of benzomorphans in rat brain homogenates. J. Pharmacol. Exp. Ther. 196: 316-322, 1976.

21. Pert, C.B. and Snyder, S.H. Opiate receptor binding: enhancement by opiate administration in vivo. Biochem. Pharmacol. 25: 847-853, 1976.

22. Pert, C.B. The opiate receptor. In: Cell Membrane Receptors for Viruses, Antigens and Antibodies, Polypeptide Hormones, and Small Molecules. Raven Press, New York, 1976, pp. 435-450.

23. Chang, J-K., Fong, B.T.W., Pert, A. and Pert, C.B. Opiate receptor affinities and behavioral effects of enkephalin: structure-activity relationship of ten synthetic peptide analogues. Life Sci. 18: 1473-1481, 1976.

24. Pert, C.B., Pert, A. and Tallman, J.F. Isolation of a novel endogenous opiate analgesic from human blood. Proc. Natl. Acad. Sci. USA 73: 2226-2230, 1976.

25. LaMotte, C., Pert, C.B. and Snyder, S.H. Opiate receptor binding in primate spinal cord: distribution and changes after dorsal root section. Brain Res. 112: 407-412, 1976.

26. Coyle, J.T. and Pert, C.B. Ontogenetic development of [3H]naloxone binding in rat brain. Neuropharmacology 15: 555-560, 1976.

27. Pert, C.B., Pert, A., Chang, J-K. and Fong, B.T.W. [D-Ala2]-Met-enkephalinamide: a potent, long-lasting synthetic pentapeptide analgesic. Science 194: 330-332, 1976.

28. Pert, C.B., Kuhar, M.J. and Snyder, S.H. Opiate receptor: autoradiographic localization in rat brain. Proc. Natl. Acad. Sci. USA 73: 3729-3733, 1976.

29. Pert, C.B., Bowie, D.L., Fong, B.T.W. and Chang, J-K. Synthetic analogues of met-enkephalin which resist enzymatic destruction. In: Opiates and Endogenous Opioid Peptides, Kosterlitz, H.W. (Ed.). Amsterdam, North Holland, 1976, pp. 79-86.

30. Pert, C.B., Snyder, S.H. and Portoghese, P.S. Correlation of opiate receptor affinity with analgetic effects of meperidine homologues. J. Med. Chem. 19: 1248-1250, 1976.

31. Pert, C.B., Snyder, S.H. and Kuhar, M.J. Opiate receptor binding in intact animals. In: Tissue Responses to Addictive Drugs, Ford, D.H. and Clouet, D. (Eds.). Spectrum Press, Holliswood, New York, 1976, pp. 89-101.

32. Weissman, B.A., Gershon, H. and Pert, C.B. Specific antiserum to leu-enkephalin and its use in a radioimmunoassay. FEBS Lett. 70: 245-248, 1976.

33. Aswanikumar, S., Corcoran, B., Schiffmann, E., Day, A.R., Freer, F.J., Showell, H.J., Becker, E.L. and Pert, C.B. Demonstration of a receptor on rabbit neutrophils for chemotactic peptides. Biochem. Biophys. Res. Comm. 74: 810-817, 1977.

34. Pert, C.B. A request for serum samples from psychiatric patients with associated autoimmune disease: is some psychosis caused by an autoimmune response to neurotransmitter receptors? Commun. Psychopharmacol. 1: 307-309, 1977.

35. Day, A.R., Radding, J., Freer, F.J., Showell, H.J., Becker, E.L., Schiffmann, E., Corcoran, B., Aswanikumar, S. and Pert, C.B. Synthesis and binding characteristics of an intrinsically radiolabeled chemotactic acyl tripeptide: N-formyl-norleucyl-leucyl-phenylalanine. FEBS Lett. 77: 291-294, 1977.

36. Pert, C.B., Bowie, D.L., Pert, A., Morell, J.L. and Gross, E. Agonist-antagonist properties of N-Allyl-[D-Ala2]-met-enkephalin. Nature 269: 73-75, 1977.

37. Pert, C.B. and Garland, B.L. The mechanism of opiate agonist and antagonist action. In: Receptors and Hormone Action, Vol. III, O’Malley, B.W. and Birnbaumer, L. (Eds.). Academic Press, New York, 1978, pp. 535-551.

38. Aswanikumar, S., Schiffmann, E., Corcoran, B.A., Pert, C.B., Morell, J.L. and Gross, E. Antibiotics and peptides with agonist and antagonist chemotactic activity. Biochem. Biophys. Res. Comm. 80: 464-471, 1978.

39. Pert, C.B. Opiate and pain pathways. Neurosci. Res. Prog. Bull. 16: 133-141, 1978.

40. Pert, A., Rosenblatt, J.E., Sivit, C., Pert, C.B. and Bunney Jr., W.E. Long-term treatment with lithium prevents the development of dopamine receptor supersensitivity. Science 201: 171-173, 1978.

41. Margules, D.L., Moisset, B., Lewis, M.J. and Pert, C.B. ß-endorphin is associated with overeating in genetically obese mice (ob/ob) and rats (fa/fa). Science 202: 988-991, 1978.

42. LaMotte, C.C., Snowman, A., Pert, C.B. and Snyder, S.H. Opiate receptor binding in rhesus monkey brain: association with limbic structures. Brain Res. 155: 374-379, 1978.

43. Allen, R.G., Herbert, E., Ninman, M., Shibuya, H. and Pert, C.B. Coordinate control of corticotropin, ß-lipotropin and ß-endorphin release in mouse pituitary cell cultures. Proc. Natl. Acad. Sci. USA 75: 4972-4976, 1978.

44. Moody, T.W., Pert, C.B., Rivier, J. and Brown, M.R. Bombesin: specific binding to rat brain membranes. Proc. Natl. Acad. Sci. USA 75: 5372-5376, 1978.

45. Jensen, R.T., Moody, T.W., Pert, C.B., Rivier, J.E. and Gardner, J.D. Interaction of bombesin and litorin with specific membrane receptors on pancreatic acinar cells. Proc. Natl. Acad. Sci. USA 75: 6139-6143, 1978.

46. Costa, T., Rodbard, D. and Pert, C.B. Interaction between the benzodiazepine receptor, the GABA receptor and a common anion channel. In: Physical Chemical Aspects of Cell Surface Events in Biological Regulation, DeLisi, C. and Blumenthal, R. (Eds.). Elsevier/North Holland, Amsterdam, 1978, pp. 37-52.

47. Rosenblatt, J.E., Pert, A., Pert, C.B., Tallman, J.F. and Bunney Jr., W.E. Possible mechanism of action of lithium: prevention of dopamine receptor supersensitivity. Fed. Proc. 37: 382, 1979.

48. Rosenblatt, J.E., Pert, C.B., Tallman, J.F., Pert, A. and Bunney Jr., W.E. The effect of imipramine and lithium on - and ß-receptor binding in rat brain. Brain Res. 160: 186-191, 1979.

49. Taylor, D.B. and Pert, C.B. Vasoactive intestinal polypeptide: specific binding to rat brain membranes. Proc. Natl. Acad. Sci. USA 76: 660-664, 1979.

50. Costa, T., Rodbard, D. and Pert, C.B. Is the benzodiazepine receptor coupled to a chloride anion channel? Nature 277: 315-316, 1979.

51. Pert, C.B. and Bowie, D.L. Behavioral manipulation of rats causes alterations in opiate receptor occupancy. In: Endorphins in Mental Health Research, Usdin, E., Bunney Jr., W.E. and Kline, N.S. (Eds.). Macmillan Press, London, 1979, pp. 93-104.

52. Bunney Jr., W.E., Pert, C.B., Klee, W., Costa, E. and Pert, A. Basic and clinical studies of endorphins. Ann. Int. Med. 91: 239-250, 1979.

53. Pert, C.B., Pert, A., Rosenblatt, J.E., Tallman, J.R. and Bunney Jr., W.E. Catecholamine receptor stabiliza-tion: a possible mode of lithium’s antimanic action. In: Catecholamines: Basic and Clinical Frontiers, Usdin, E. (Ed.). Pergamon Press, New York, 1979, pp. 583-585.

54. Moody, T.W. and Pert, C.B. Bombesin-like peptides in rat brain: quantitation and biochemical characterization. Biochem. Biophys. Res. Comm. 90: 7-14, 1979.

55. Rosenblatt, J.E., Pert, C.B., Colison, J., van Kammen, D.P. and Bunney Jr., W.E. Measurement of serum neuroleptic concentration by radioreceptor assay: concurrent assessment of clinical psychosis ratings. Commun. Psychopharmacol. 3: 153-158, 1979.

56. Rodbard, D., Costa, T. and Pert, C.B. Is the benzodiazepine receptor coupled to a anion channel? Reply in Nature 280: 173-174, 1979.

57. Taylor, D.P., Herkenham, M. and Pert, C.B. Localization of specific high-affinity binding of vasoactive intestinal polypeptide (VIP) in rat brain. In: Peptides: Structure and Biological Function, Gross, E. and Meienhofer, J. (Eds.). Pierce Chemical, Rockford, IL, 1979, pp. 912-920.

58. Moody, T.W., Pert, C.B. and Jacobowitz, D. Bombesin-like peptides: regional distribution in rat brain. In: Peptides: Structure and Biological Function, Gross, E. and Meienhofer, J. (Eds.). Pierce Chemical, Rockford, IL, 1979, pp. 865-872.

59. Pert, C.B., Taylor, D.P., Pert, A., Herkenham, M.A. and Kent, J.L. Biochemical evidence for type 1 and type 2 opiate receptors. In: Peptides: Structure and Biological Function, Gross, E. and Meienhofer, J. (Eds.). Pierce Chemical, Rockford, IL, 1979, pp. 845-851.

60. Bunney Jr., W.E., Pert, A., Rosenblatt, J.E. and Pert, C.B. Some biological considerations of the mode of action of lithium in the treatment of affective illness. Arch. Gen. Psychiatr. 36: 898-901, 1979.

61. Peaslee, M.H., Moisset, B., Shibuya, H. and Pert, C.B. Increase in pituitary melanocyte-stimulating hormone activity of genetically obese (ob/ob) mice. Experientia 36: 133, 1980.

62. Pert, C.B. and Taylor, D.P. Type 1 and Type 2 opiate receptors: a subclassification scheme based upon GTP’s differential effects on binding. In: Endogenous and Exogenous Opiate Agonists and Antagonists, Way, E.L. (Ed.). Pergamon Press, New York, 1980, pp. 87-90.

63. Moody, T.W., Thoa, N.B., O’Donohue, T.L. and Pert, C.B. Bombesin-like peptides in rat brain: localization in synaptosomes and release from hypothalamic slices. Life Sci. 26: 1707-1712, 1980.

64. Naber, D., Pickar, D., Dionne, R.A., Bowie, D.L., Ewels, B., Moody, T.W., Soble, M.G. and Pert, C.B. Assay of endogenous opiate receptor ligands in human CSF and plasma. Substance and Alcohol Actions/Misuse 1: 83-91, 1980.

65. Shibuya, H., Gale, K. and Pert, C.B. Supersensitivity to GABA’s effect on benzodiazepine receptors develops after striatonigral lesions. Eur. J. Pharmacol. 62: 243-244, 1980.

66. Pert, C.B., Taylor, D.P., Pert, A., Herkenham, M.A. and Kent, J.L. Biochemical and autoradiographical evidence for type 1 and type 2 opiate receptors. In: Advances in Biochemical Psychopharmacology, Neural Peptides and Neuronal Communication, Costa, E. and Travucchi, M. (Eds.). Raven Press, New York, 1980, pp. 581-589.

67. Pert, A., Moody, T.W., Pert, C.B., DeWald, L.A. and Rivier, J. Bombesin: receptor distribution in brain and effects on nociception and locomotor activity. Brain Res. 193: 209-220, 1980.

68. Herkenham, M. and Pert, C.B. In vitro autoradiography of opiate receptors in rat brain suggests loci of “opiatergic” pathways. Proc. Natl. Acad. Sci. USA 77: 5532-5536, 1980.

69. Pickar, D., Cutler, N.R., Naber, D., Post, R.M., Pert, C.B. and Bunney Jr., W.E. Plasma opioid activity in manic-depressive illness. Lancet, April 26, 1980, p. 937.

70. Rosenblatt, J.E., Shore, D., Wyatt, R.J. and Pert, C.B. Increased renal neuroleptic binding in spontaneously hypertensive rats. Eur. J. Pharmacol. 67: 317-320, 1980.

71. DiMicco, J.A., Kopin, I.J. and Pert, C.B. Evaluation of ß-adrenergic receptor status by plasma sampling in living rats. In: Proceedings of the Conference on the Psychopharmacology and Biochemistry of Neurotransmitter Receptors, Yamamura, H.I., Olsen, R.W. and Usdin, E. (Eds.). Elsevier/North Holland, Amsterdam, 1980, pp. 237-246.

72. Pert, C.B. Type 1 and Type 2 opiate receptor distribution in rat brain–what does it tell us? In: Neuro-secretion and Brain Peptides, Martin J.B., Reichlin, S. and Bick, K.L. (Eds.). Raven Press, New York, 1981, pp. 117-131.

73. Pert, C.B. Opiate receptors for the brain’s own morphine. J. Surg. Prac. 10: 10-18, 1981.

74. Recant, L., Voyles, N.R., Luciano, M. and Pert, C.B. Naltrexone reduces weight gain, alters “ß-endorphin”, and reduces insulin output from pancreatic islets of genetically obese mice. Peptides 1: 309-313, 1981.

75. Lewis, M.E., Mishkin, M., Bragin, E., Brown, R.M., Pert, C.B. and Pert, A. Opiate receptor gradients in monkey cerebral cortex: correspondence with sensory processing hierarchies. Science 211: 1166-1169, 1981.

76. Naber, D., Cohen, R.M., Pickar, D., Kalin, N.H., Davis, G., Pert, C.B. and Bunney Jr., W.E. Episodic secretion of opioid activity in human plasma and monkey CSF: evidence for a diurnal rhythm. Life Sci. 28: 931-935, 1981.

77. Herkenham, M. and Pert, C.B. Mosaic distribution of opiate receptors, parafascicular projects and acetylcholinesterase in the rat striatum. Nature 291: 415-418, 1981.

78. Pert, A., Pert, C.B., Davis, G. and Bunney Jr., W.E. Opiate peptides and brain function. In: Handbook of Biological Psychiatry, Part IV, van Praag, H.M. (Ed.). Marcel Dekker, New York, 1981, pp. 547-582.

79. Moody, T.W., Taylor, D.P. and Pert, C.B. Effects of guanine nucleotides on CNS neuropeptide receptors. J. Supramol. Struct. 15: 153-159, 1981.

80. Pert, C.B. and Herkenham, M. From receptors to brain circuitry. In: Biochemistry of Taste and Olfaction, Cagan, R. (Ed.). Academic Press, New York, 1981, pp. 511-527.

81. Quirion, R., Hammer Jr., R.P., Herkenham, M. and Pert, C.B. Phencyclidine (angel dust)/”opiate” receptor: its visualization by tritium-sensitive film. Proc. Natl. Acad. Sci. USA 78: 5881-5885, 1981.

82. Bowen, W.D., Gentleman, S., Herkenham, M. and Pert, C.B. Interconverting µ and -forms of the opiate receptor in rat striatal patches. Proc. Natl. Acad. Sci. USA 78: 4818-4822, 1981.

83. Costa, T., Russell, L., Pert, C.B. and Rodbard, D. Halide- and -aminobutyric acid-induced enhancement of diazepam receptors in rat brain. Reversal by disulfonic stilbene blockers of anion channels. Mol. Pharmacol. 20: 470-476, 1981.

84. Pert, A., Dionne, R., Ng, L., Bragin, E., Moody, T.W. and Pert, C.B. Alterations in rat central nervous system endorphins following transauricular electro-acupuncture. Brain Res. 224: 83-93, 1981.

85. Quirion, R., Bowen, W.D. and Pert, C.B. µ,  and k opiate receptors: interconvertible forms of the same receptor. In: Advances in Endogenous and Exogenous Opioids. Proceedings of the International Narcotic Research Conference. Kodansha Ltd., Kyoto, Japan, 1981, pp. 63-65.

86. Moody, T.W., Pert, C.B., Gazdar, A.F., Carney, D.N. and Minna, J.D. High Levels of intracellular bombesin characterize human small-cell lung carcinoma. Science 214: 1246-1248, 1981.

87. Quirion, R., Rice, K.C., Skolnick, P., Paul, S. and Pert, C.B. Stereospecific displacement of [3H]phencyclidine (PCP) receptor binding by an enantiomeric pair of PCP analogs. Eur. J. Pharmacol. 74: 107-108, 1981.

88. Quirion, R. and Pert, C.B. Dynorphins: similar relative potencies on mu, delta and kappa opiate receptors. Eur. J. Pharmacol. 76: 467-468, 1981.

89. Kent, J.L., Pert, C.B. and Herkenham, M. Ontogeny of opiate receptors in rat forebrain: visualization by in vitro autoradiography. Develop. Brain Res. 2: 487-504, 1982.

90. Pert, C.B. and Schumacher, U.K. Plasma bombesin concentrations in patients with extensive small cell carcinoma of the lung. Letter to the Editor, Lancet, February 27, 1982, p 509.

91. Quirion, R., Hammer Jr., R.P, Herkenham, M. and Pert, C.B. Autoradiographic localization of the phencyclidine/sigma “opiate” receptor in rat brain. NIDA Research Monography, 1982, pp. 178-183.

92. Hammer Jr., R.P., Herkenham, M., Pert, C.B. and Quirion, R. Correlation of regional brain metabolism with receptor localization during ketamine “anesthesia”: a combined autoradiographic [3H]2-deoxy-D-glucose, receptor binding technique. Proc. Natl. Acad. Sci. USA 79: 3067-3070, 1982.

93. Bowen, W. and Pert, C.B. Conformational mobility of opiate receptors: sulfhydryl modification alters ion-induced µ/ ligand selectivity shifts in rat striatal sections. Cell. Mod. Neurochem. 2: 115-128, 1982.

94. Quirion, R., Kiso, Y. and Pert, C.B. Syndyphalin SD-25: a highly selective ligand for µ opiate receptors: FEBS Lett. 141: 203-206, 1982.

95. Quirion, R. and Pert, C.B. Amantadine modulates phencyclidine binding sites sensitivity in rat brain. Experientia 38: 955-956, 1982.

96. Olgiati, V., Quirion, R., Bowen, W.D. and Pert, C.B. Characterization of type 2 opiate receptors. Life Sci. 31: 1675-1678, 1982.

97. Quirion, R. and Pert, C.B. Certain calcium antagonists are potent displacers of [3H]phencyclidine (PCP) binding in rat brain. Eur. J. Pharmacol. 83: 155-156, 1982.

98. Bowen, W.D., Pert, C.B. and Pert, A. Nigral 6-hydroxy-dopamine lesions equally decrease mu and delta opiate binding to striatal patches: further evidence for a conformationally malleable type 1 opiate receptor. Life Sci. 31: 1679, 1982.

99. Herkenham, M. and Pert, C.B. Light microscopic localization of brain opiate receptors: a general autoradiographic method which preserves tissue quality. J. Neurosci. 2: 1129-1149, 1982.

100. Edley, S.M., Hall, L., Herkenham, M. and Pert, C.B. Evolution of striatal opiate receptors. Brain Res. 249: 184-188, 1982.

101. LeRoith, D., Liotta, A.S., Roth, J., Shiloach, J., Lewis, M.E., Pert, C.B. and Krieger, D.T. Corticotropin and ß-endorphin-like materials are native to unicellular organisms. Proc. Natl. Acad. Sci. USA 79: 2086-2090, 1982.

102. Quirion, R., Bowen, W.D., Herkenham, M. and Pert, C.B. Visualization and solubilization of rat brain opiate receptors with a “k” ligand selectivity pattern. Cell. Mol. Neurobiol. 2: 333-346, 1982.

103. Quirion, R., Bayorh, M.A., Zerbe, R.L. and Pert, C.B. Chronic phencyclidine treatment decreases phencyclidine and dopamine receptors in rat brain. Pharmacol. Biochem. Behav. 17: 699-702, 1982.

104. Quirion, R., Gaudreau, P., St-Pierre, S., Rioux, F. and Pert, C.B. Autoradiographic distribution of [3H]neurotensin receptors in rat brain: visualization by tritium-sensitive film. Peptides 3: 757-763, 1982.

105. Quirion, R., Larsen, T.A., Calne, D., Chase, T., Rioux, F., St-Pierre, S., Evarist, H., Pert, A. and Pert, C.B. Analysis of [3H]neurotensin receptors by computerized densitometry: visualization of central and peripheral neurotensin receptors. Annals of the New York Academy of Science, 1982, pp. 415-417.

106. Pert, C.B., Costa, T., Rodbard, D. and Pert, A. In vitro effects on anions and temperature: clues to benzodiazepine receptor function. In: Pharmacology of Benzodiazepines, Usdin, E. (Ed.). Macmillian Press, Ltd., 1982, pp. 561-566.

107. Pert, C.B. and Quirion, R. The phencyclidine receptor. Trends Pharmacol. Sci. 4: 12-13, 1983.

108. Altura, B.T., Quirion, R., Pert, C.B. and Altura, B.M. Phencyclidine (angel dust) analogs and sigma opiate benzomorphans cause cerebral arterial spasm. Proc. Natl. Acad. Sci. USA 80: 865-869, 1983.

109. Gaudreau, P., Quirion, R., St-Pierre, S. and Pert, C.B. Tritium-sensitive film autoradiography of [3H]-cholecystokinin-5/pentagastrin receptors in rat brain. Eur. J. Pharmacol. 87: 173-174, 1983.

110. Farrell, P.A., Gates, W.G., Morgan, W.P. and Pert, C.B. Plasma leucine enkephalin-like radioreceptor activity and tension-anxiety before and after competitive running. In: Biochemistry of Exercise, Knuttgen, H.G., Vogel, J.A. and Poortmans, J. (Eds.). Human Kinetics Publishers, Champaign, IL, 1983, pp. 637-644.

111. Quirion, R., Shults, C.W., Moody, T.W., Wolf, S.S., Jensen, R.T., Pert, C.B., Chase, T.N. and O’Donohue, T.L. Autoradiographic localization of substance P (SP) receptors in rat brain: a comparison of binding properties of [3H]SP, [125I]physalaemin. In: Substance P, Powell, D. and Srabranek, P. (Eds.). Boole Press, Dublin, Ireland, 1983, pp. 55-56.

112. Quirion, R., Shults, C.W., Moody, T.W., Pert, C.B., Chase, T.N. and O’Donohue, T.L. Autoradiographic distribution of substance P receptors in rat central nervous system. Nature 303: 714-716, 1983.

113. Quirion, R. and Pert, C.B. Modulation of phencyclidine receptor sensitivity. In: Proceedings of the 44th Annual Meeting Committee on Problem of Drug Dependence 217: 217-223, 1983.

114. Lewis, M.E., Pert, A., Pert, C.B. and Herkenham, M. Opiate receptor localization in rat cerebral cortex. J. Comp. Neurol. 216: 339-358, 1983.

115. Gentleman, S., Parenti, M., Neff, N.H. and Pert, C.B. Inhibition of dopamine-activated adenylate cyclase and dopamine binding by opiate receptors in rat straitum. Cell. Mol. Neurobiol. 3: 17-26, 1983.

116. Rice, K.C., Konicki, P.E., Quirion, R., Burke Jr., T.R. and Pert, C.B. Synthesis and pharmacological characterization of ()-5,9--dimethyl-2-[2-(4-fluorophenyl)-ethyl]-2′-hydroxy-6,7-benzomorphan (Fluorophan), a ligand suitable for visualization of opiate receptors in vivo. J. Med. Chem., 1643-1645, 1983.

117. Quirion, R., Herkenham, M., O’Donohue, T.L. and Pert, C.B. Autoradiographic localization of 3H-ethylketo-cycazocine binding sites in rat brain. In: Analgesia and Enkephalinases, Boigegrain, R., Cros, J., Morre, M., Muyard, J.P. and Roncucci, R. (Eds.). Sanofi Publishers, Montpellier, France, 1984, pp. 333-340.

118. Quirion, R., O’Donohue, T.L., Everist, H., Pert, A. and Pert, C.B. Phencyclidine receptors and possible existence of an endogenous ligand. In: Phencyclidine and Related Arlcyclohexylamines: Present and Future Applications, Kamenka, J.M., Domino, E.F. and Geneste, P. (Eds.). NPP Books, Ann Arbor, MI, 1983, pp. 667-684.

119. Gaudreau, P., Quirion, R., St-Pierre, S. and Pert, C.B. Characterization and visualization of cholecystokinin receptors in rat brain using [3H]pentagastrin. Peptides 4: 755-762, 1983.

120. Gaudreau, P., Morell, J.L., St-Pierre, S., Quirion, R. and Pert, C.B. Cholecystokinin octapeptide fragments: synthesis and structure-activity relationship. In: Peptides: Structure and Function. Proceedings of the Eighth American Peptide Symposium, Hruby, V. and Rich, D. (Eds.). Pierce Chemical, Rockford, IL, 1983, pp. 441-444.

121. O’Donohue, T.L., Pert, C.B., Pert, A., French, E.D., Everist, H. and Quirion, R. Evidence for an endogenous central nervous system ligand for the phencyclidine receptor. In: Peptides: Structure and Function. Proceedings of the Eight American Peptide Symposium, Hruby, V. and Rich D. (Eds.). Pierce Chemical, Rockford, IL, 1983, pp. 433-436.

122. McLean, S., Skirboll, L. and Pert, C.B. Opiatergic projection from the bed nucleus to the habenula: demonstration by a novel radioimmunohistochemical method. Brain Res. 278: 255-257, 1983.

123. Quirion, R. and Pert, C.B. Properties of the phen-cyclidine (PCP) receptors. Prog. Neuropsycho-pharmacol. Biol. Psychiatry 7: 451-456, 1983.

124. Quirion, R., Weiss, A.S. and Pert, C.B. Comparative pharmacological properties and autoradiographic distribution of [3H]ethylketocyclazocine binding sites in rat and guinea pig brain. Life Sci. 33(1): 183-186, 1983.

125. Rothman, R.B., Schumacher, U.K. and Pert, C.B. Binding of radiolabeled opiates to slide-mounted sections of molded minced rat brain: a novel method for conducting radioreceptor assays. Neuropeptides 3: 493-499, 1983.

126. Rothman, R.B., Bowen, W.D., Schumacher, U.K. and Pert, C.B. Effect of ß-FNA on opiate receptor binding: preliminary evidence for two types of µ receptors. Eur. J. Pharmacol. 95: 147-148, 1983.

127. Rothman, R.B., Bowen, W.D., Bykov, V., Schumacher, U.K. and Pert, C.B. Preparation of rat brain membranes greatly enriched with either type-I-delta or type-II-delta opiate binding sites using site directed alkylating agents: evidence for a two-site allosteric model. Neuropeptides 4: 201-215, 1984.

128. Rothman, R.B., Danks, J.A. and Pert, C.B. Ionic conditions differentially affect 3H-DADL binding to type-I and type-II opiate delta receptors in vitro. Neuropeptides 4: 261-268, 1984.

129. Rothman, R.B., Pert, C.B., Jacobson, A.E., Burke Jr., T.R. and Rice, K.C. Morphine noncompetitively inhibits [3H]leucine enkephalin binding to membranes lacking type-II delta binding sites: evidence for a two-site allosteric model. Neuropeptides 4: 257-260, 1984.

130. Ruff, M.R. and Pert, C.B. Small cell carcinoma of the lung: macrophage-specific antigens suggest hemopoietic stem cell origin. Science 225: 1034-1036, 1984.

131. Rothman, R.B., Herkenham, M., Pert, C.B., Liang, T. and Cascieri, M.A. Visualization of rat brain receptors for the neuropeptide, substance P. Brain Res. 309: 47-54, 1984.

132. Seeger, T.F., Sforzo, G.A., Pert, C.B. and Pert, A. In vivo autoradiography: visualization of stress-induced changes in opiate receptor occupancy in the rat brain. Brain Res. 305: 303-311, 1984.

133. Rothman, R.B., Schumacher, U.K. and Pert, C.B. Effect of ß-FNA on opiate receptor binding. J. Neurochem. 43: 1197-1200, 1984.

134. Weber, R.J. and Pert, C.B. Opiatergic modulation of the immune system. In: Central and Peripheral Endorphins – Basic and Clinical Aspects, Muller, E.E. and Genazzani, A.R. (Eds.). Raven Press, New York, 1984, pp. 35-42.

135. Rothman, R.B., Danks, J.A., Jacobson, A.E., Burke Jr., T.R., Rice, K.C. and Pert, C.B. Tritiated-6-fluoro-desoxy-oxymorphone: a highly selective ligand for the opiate mu receptor whose binding is characterized by low nonspecific binding. Neuropeptides 4: 311-317, 1984.

136. Finkel, M.S., Quirion, R., Pert, C.B. and Patterson, R.E. Characterization and autoradiographic distribution of the ß-adrenergic receptor in the rat lung. Pharmacology 29: 247-254, 1984.

137. Rothman, R.B., Danks, J.A., Herkenham, M., Cascieri, M.A., Liang, T. and Pert, C.B. Autoradiographic localization of a novel peptide binding site in rat brain using the substance P analog, eledoisin. Neuropeptides 4: 343-349, 1984.

138. Pert, C.B., Danks, J.A., Channing, M.A., Eckelman, W.C., Larson, S.M., Bennett, J.M., Burke Jr., T.R. and Rice, K.C. [3H]-3-Acetylcyclofoxy: a useful probe for the visualization of opiate receptors in living animals. FEBS Lett. 177: 281-286, 1984.

139. Clarke, P.B.S., Pert, C.B. and Pert, A. Autoradiographic distribution of nicotine receptors in rat brain. Brain Res. 323: 390-395, 1984.

140. DeLisi, L.E., Weber, R.J. and Pert, C.B. Are there antibodies against brain in sera from schizophrenic patients? Review and prospectus. Biological Psychiatry 20: 110-115, 1985.

141. Burke Jr., T.R., Rice, K.C. and Pert, C.B. Probes for narcotic receptor mediated phenomena 11. Synthesis of 17-methyl and 17-cyclopropylmethyl-3,14-dihydroxy-4,5-6ß-fluoromorphinans (foxy and cyclofoxy) as models of opioid ligands suitable for positron emission transaxial tomography. Heterocycles 23: 99-106, 1985.

142. Ruff, M.R., Wahl, S.M., Mergenhagen, S. and Pert, C.B. Opiate receptor-mediated chemotaxis of human monocytes. Neuropeptides 5: 363-366, 1985.

143. McLean, S., Skirboll, L.R. and Pert, C.B. Comparison of substance P and enkephalin in rat brain: an overview using radioimmunocytochemistry. J. Neurosci. 14: 837-852, 1985.

144. Rothman, R.B., Bowen, W.D., Herkenham, M., Jacobson, A.E., Rice, K.C. and Pert, C.B. A quantitative study of [3H]D-Ala2-D2-leu5-enkephalin binding to rat brain membranes: evidence that oxymorphone is a noncompetitive inhibitor. Mol. Pharmacol. 27: 399-408, 1985.

145. Clarke, P.B.S., Schwartz, R.D., Paul, S.M., Pert, C.B. and Pert, A. Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125]--bungarotoxin. J. Neurosci. 5: 1307-1315, 1985.

146. Pert, C.B., Ruff, M.R., Weber, R.J. and Herkenham, M. Neuropeptides and their receptors: a psychosomatic network. J. Immunol. 135: 820s-826s, 1985.

147. Hill, J.M., Ruff, M.R., Weber, R.J. and Pert, C.B. Transferrin receptors in rat brain: their neuropeptide-like pattern and relationship to iron distribution. Proc. Natl. Acad. Sci. USA 82: 4553-4557, 1985.

148 Gaudreau, P., St-Pierre, S., Peret, C.B., Quiron,R. Cholecystokinin receptors in mammalian brain. A comparative characterization and visulaization. Ann. NY Acad. Sci. 448:198-219, 1985.

149. Fabbri, A., Gnessi, L., Moretti, C., Pert, C.B., Pert, A. and Fraioli, F. The calcitonin neuropeptide: clinical and experimental studies. In: Calcitonin: Chemistry, Physiology, Pharmacology and Clinical Aspects, Pecile, A. (Ed.). Elsevier/North Holland, Amsterdam, 1985, pp. 397-409.

150. Ruff, M.R., Pert, C.B., Weber, R.J., Wahl, L.M., Wahl, S.M. and Paul, S.M. Benzodiazepine receptor-mediated chemotaxis of human monocytes. Science 229: 1281-1283, 1985.

151. Pert, C.B. Neuropeptides, receptors and emotion. Cybernetics 1: 33-34, 1985.

152. Fabbri, A., Fraioli, F., Pert, C.B. and Pert, A. Calcitonin receptors in the rat mesencephalon mediate its analgesic actions: autoradiographic and behavioral analyses. Brain Res. 343: 205-215, 1985.

153. Ruff, M.R. and Pert, C.B. Origin of human small cell lung cancer. Science 229 (Reply): 679-680, 1985.

154. Gnessi, L., Ruff, M.R., Fraioli, F. and Pert, C.B. Demonstration of receptor-mediated chemotaxis by human spermatozoa. Exp. Cell Res. 161: 219-230, 1985.

155. Ruff, M.R., Schiffmann, E., Terranova, V. and Pert, C.B. Neuropeptides are chemoattractants for human macrophages and tumor cells: a mechanism for metastasis. Clin. Immunol. and Immunopath. 37: 387-396, 1985.

156. Ruff, M.R., Wahl, S.M. and Pert, C.B. Substance P receptor-mediated chemotaxis of human monocytes. Peptides 6: 107-111, 1985.

157. McLean, S., Bannon, M.J., Zamir, N., Pert, C.B. Comparison of the substance P and dynorphin-containing projections to the substantia nigra: a radioimmunocytochemical and biochemical study. Brain Res. 361: 185-192, 1985.

158. Hohmann, C.F., Pert, C.B., Ebner, F.F. Development of cholinergic markers in mouse forebrain. II Muscarinic receptor binding in cortex. Brain Res. 355: 243-253, 1985.

159. Patel, J., Fabbri, A., Pert, C.B., Gnessi, L. et al. Calcitonin inhibits the phosphorylation of various proteins in rat brain synaptic membranes. Biochem. Biophys. Res. Commun. 130: 669-676, 1985.

160. Ruff, M.R. and Pert, C.B. Neuropeptides are chemo-attractants for human monocytes and tumor cells: a basis for mind-body communication. In: Enkephalins and Endorphins Stress and Immune System, Plotnikoff, N.P., Faith, R.E., Urgo, A.J. and Good, R.A. (Eds.). Plenum Publishing Corporation, New York, 1986, pp. 387-398.

161. Hill, J.M., Lesniak, M.A., Pert, C.B. and Roth, J. Autoradiographic localization of insulin receptors in rat brain: prominence in olfactory and limbic areas. Neurosci. 17: 1127-1138, 1986.

162. Ruff, M.R., Farrar, W.L. and Pert, C.B. Gamma interferon and GM-CSF promote antigenic modulation and growth inhibition characteristic of myeloid differentiation in small cell lung cancer cell lines. Proc. Natl. Acad. Sci. USA 83: 6613-6617, 1986.

163. Hill, J.M., Farrar, W.L. and Pert, C.B. Localization of the T4 antigen/AIDS virus receptor in monkey and rat brain: prominence in cortical regions. Psychopharmacology Bulletin 22: 686-694, 1986.

164. Wiedermann, C.J., Goldman, M.E. and Pert, C.B. Chromatographic analysis of gastrin-releasing peptide in heat inactivated fetal calf serum. Cell and Tissue Kinetics 19: 467-470, 1986.

165. Pert, C.B., Hill, J.M., Ruff, M.R., Berman, R.M., Robey, W.G., Arthur, L.O., Ruscetti, F.W. and Farrar, W.L. Octapeptides deduced from the neuropeptide receptor-like pattern of antigen T4 in brain potently inhibit human immunodeficiency virus receptor binding and t-cell infectivity. Proc. Natl. Acad. Sci. USA 83: 9254-9258, 1986.

166. Pert, C.B. and Ruff, M.R. Peptide T[4-8]: a pentapeptide sequence in the AIDS virus envelope which blocks infectivity is essentially conserved across nine isolates. Clin. Neuropharmacol. 9(4): S198, 1986.

167. Wiedermann, C.J., Sertl, K. and Pert, C.B. Substance P receptors in rat spleen: characterization and autoradiographic distribution. Blood 68: 1398-1401, 1986.

168. Gnessi, L., Fabbri, A., Silvestroni, L., Moretti, C., Fraioli, F., Pert, C.B. and Isidori, A. Evidence for the presence of specific receptors for N-formyl chemotactic peptides on human spermatozoa. J. Clin. Endocrinol. Metab. 4: 841-846, 1986.

169. Wiedermann, C.J., Goldman, M.E., Sertl, K., Plutchok, J.J., Kaliner, M.A., Johnston-Early, A., Cohen, M.H., Ruff, M.R. and Pert, C.B. Bombesin in human and guinea pig alveolar macrophages. J. Immunol. 137: 3928-3932, 1986.

170. Pert, C.B. The wisdom of the receptors: neuropeptides, the emotions, and bodymind. Advances 3: 8-16, 1986.

171. Sforzo, G.A., Seeger, T.F., Pert, C.B., Pert, A., and Dotson, C.O. In vivo opiod receptor occupation in the rat brain following excercise. Med. Sci. Sports Excer. 18: 380-384, 1986.

172. Hill, J.M., Farrar, W.L., Pert, C.B. Autoradiographic localization of T4 antigen, the HIV receptor, in human brain. Int’l J. Neurosci. 29: 687-693, 1986.

173. Ostrowski, N.L., Burke, T., Rice, K.C., Pert, A. and Pert, C.B. The pattern of [3H]cyclofoxy retention in rat brain after in vivo injection corresponds to the in vitro opiate receptor distribution. Brain Res. 402: 275-286, 1987.

174. Ruff, M.R., Martin, B.M., Ginns, E.I., Farrar, W.L., Wahl, S.M. and Pert, C.B. CD4 receptor binding peptides that block HIV infectivity cause human monocyte chemotaxis: relationship to vasoactive intestinal polypeptide. FEBS Lett. 211: 17-22, 1987.

175. Wetterberg, L., Alexius, B., Saaf, J., Sonnerborg, A., Britton, S. and Pert, C. Peptide T in treatment of AIDS. Lancet, January 17, 1987, p. 159.

176. Farrar, W.L., Kilian, P., Hill, J.M., Ruff, M.R. and Pert, C.B. Visualization of cytokine and virus receptors common to the immune and central nervous system. Lymphokine Res. 6: 29-34, 1987.

177. Ostrowski, N.L., Hill, J.M., Pert, C.B. and Pert, A. Autoradiographic visualization of sex difference in the pattern and density of opiate receptors. Brain Res. 421: 1-13, 1987.

178. Wiedermann, C.J., Sertl, K. and Pert, C.B. High-affinity substance P binding sites in rat esophagus plexus submucosus. Am. J. Physiol. 253: R167-R171, 1987.

179. Knight, J.G., Knight, A. and Pert, C.B. Is schizophrenia a virally-triggered anti-receptor autoimmune disease? In: Biological Perspectives in Schizophrenia, Helmchen, H. and Henn, F.A. (Eds.). John Wiley and Sons, Ltd., New York, 1987, pp. 107-124.

180. Wiedermann, C.J., Sertl, K. and Pert, C.B. Neuropeptides and the immune system: substance P receptors in bronchus-associated lymphoid tissue of rat. Annals of the NY Acad. Sci. 496: 205-210, 1987.

181. Sacerdote, P., Ruff, M.R. and Pert, C.B. Vasoactive intestinal peptide: a ligand for the CD4 (T4)/human immunodeficiency virus receptor present on brain and immune cells. J. Neurosci. Res. 18: 102-107, 1987.

182. Weber, R.J., Hill, J.M. and Pert, C.B. Regional distribution and density of Thy 1.1 in rat brain and its relation to subpopulations of neurons. J. Neuroimmunol. 17: 137-145, 1987.

183. Pert, C.B., Smith, C.C., Ruff, M.R. and Hill, J.M. AIDS and its dementia as a neuropeptide disorder: role of VIP receptor blockade by human immunodeficiency virus (HIV) envelope. Annals of Neurology 23: S71-S73, 1987.

184. Hill, J.M., Lesniak, M.A., Rojeski, M., Pert, C.B. and Roth, J. Receptors for insulin and insulin related peptides in the CNS: studies of localization in rat brain. In: Insulin, Insulin-Like Growth Factors, and Their Receptors in the Central Nervous System, Raizada, M.K. and Phillips, M.I. (Eds.). Plenum Press, New York, 1987, pp. 261-267.

185. Ruff, M.R., Hallberg, P.L., Hill, J.M., and Pert, C.P. Peptide T4-8 is core HIV envelope sequence required for CD4 receptor attachment. The Lancet, September 26, 1987, p. 751.

186. Ruff, M.R. and Pert, C.B. Human monocyte chemotaxis to neuropeptides. Adv. Biochem. Psychopharmacol. 43: 247-260, 1987.

187. Gaudreau, P., St-Pierre, S., Pert, C.B., Quirion, R. Structure-activity studies of C- and N-terminal fragments of cholecystokinin 26-33 in guinea pig isolated tissues. Neuropeptides 10: 9-18, 1987.

188. Farrell, P.A., Gustafson, A.B., Morgan, W.P., Pert, C.B. Enkephalins, catecholamines, and psychological mood alterations: effects of prolonged excercise. Med. Sci. Sports Exerc. 19: 347-353, 1987.

189. Farrar, W.L., Hill, J.M., Ruff, M.R., Pert, C.B. Autoradiographic distribution of IL-1 receptors in rat brain. J. Immunol. 139: 459-463, 1987.

190. Sacerdote, P., Ruff, M.R., and Pert, C.P. VIP¬1-12 is a ligand for the CD4/Human Immunodeficiency receptor. Annals of the N.Y. Acad. of Sci., p. 574, 1988.

191. Hill, J.M., Ruff, M.R. and Pert, C.B. AIDS as a neuropeptide disorder: Peptide T,VIP and the HIV receptor. Psychopharma. Bull. 24: 315-319, 1988.

192. Pert, C.B., Smith, C.C., Ruff, M.R. and Hill, J.M. AIDS and its dementia as a neuropeptide disorder: role of VIP receptor blockade by human immunodeficiency virus envelope. Ann. Neurol. 23, s71-s73, 1988.

193. Wiedermann, C.J., Sertl, K., Zipser, B., Hill, J.M. and Pert, C.B. Vasoactive intestinal peptide receptors in rat spleen and brain: a shared communication network. Peptides 9: 21-28, 1994.

194. Sacerdote, P., Ruff, M.R. and Pert, C.B. Cholecystokinin and the immune system: receptor-mediated chemotaxis of human and rat monocytes. Peptides 9: 29-34, 1988.

195. Hill, J.M., Lesniak, M.A. and Pert, C.B. Co-localization of IGF-II receptors, IL-1 receptors and Thy 1.1 in rat brain. Peptides 9: 91-96, 1988.

196. Ruscetti, F.W., Farrar, W.L., Hill, J.M. and Pert, C.B. Visualization of a differentiation antigen of human helper T lymphocytes in primate brain. Peptides 9: 97-104, 1988.

197. O’Neill, J.B., Pert, C.B., Ruff, M.R., Smith, C.C., Higgins, W.J. and Zipser, B. Identification and characterization of the opiate receptor in the ciliated protozoan, Tetrahymena. Brain Res. 450: 303-315, 1988.

198. Wiedermann, C.J., Jelesoff, N.E., Pert, C.B. and Hill, J.M. Distribution of epidermal growth factor receptors in rat brain. Peptides, in press.

199. Ruff, M.R., Sacerdote, P., Wiedermann, C.J. and Pert, C.B. Neuropeptide receptors are shared components of nervous and immune systems. In: Neuropeptides and Stress, Hans Selye Symposia on Neuroendocrinology and Stress, Tache´, Y., Morely, J. and Brown, M (Eds.). Springer-Verlag, New York, 1989, pp. 235-246.

200. Hill, J.M., Ruff, M.R., Lesniak, M.A., Roth, J. and Pert, C.B. Molecular components common to the immune system and neurons: growth factors and their receptors. In: Physiological, Neuropsychiatric, and Substance Abuse Aspects of AIDS. Vol. 44. Advances in Biochemical Psychopharmacology, Bridge, T.P., Mirsky, A.F. and Goodwin, F.K. (Eds.). Raven Press, New York, 1988, pp. 21-33.

201. Pert, C.B., Ruff, M.R., Ruscetti, F., Farrar, W.L. and Hill, J.M. HIV receptor in brain and deduced peptides that block viral infectivity. In: Physiological, Neuropsychiatric, and Substance Abuse Aspects of AIDS. Vol. 44. Advances in Biochemical Psychopharmacology, Bridge, T.P., Mirsky, A.F. and Goodwin, F.K. (Eds.). Raven Press, New York, 1988, pp. 73-83.

202. Farrar, W.L., Ruff, M.R., Hill, J.M. and Pert, C.B. Characterization of IL-1 receptor in brain. In: Physiological, Neuropsychiatric, and Substance Abuse Aspects of AIDS. Vol. 44. Advances in Bochemical Psychopharmacology, Bridge, T.P., Mirsky, A.F. and Goodwin, F.K. (Eds.). Raven Press, New York, 1988, pp. 35-44.

203. Pert, C.B., Knight, J.G., Laing, P. and Markwell, M.A.K. Scenarios for a viral etiology of schizophrenia. Schizophrenia Bulletin 14: 243-247, 1988.

204. Sertl, K., Wiedermann, C.J., Kowalski, M.L., Hurtado, S., Plutchok, J., Linnoila, I., Pert, C.B. and Kaliner, M.A. Substance P: The relationship between receptor distribution in rat lung and the capacity of substance P to stimulate vascular permeability. Am. Rev. Respir. Dis. 138: 151-159, 1988.

205. Pert, C. and Dienstfrey, H. The neuropeptide network. In: Annals of the New York Academy of Sciences Vol. 521. Neuroimmunomodulation: Interventions in aging and cancer. First Stromboli Conference on Aging and Cancer, Pierpaoli, W. and Spector, N.H. (Eds.). New York Academy of Sciences, New York, 1988, pp. 189-194.

206. Brenneman, D.E., Westbrook, G.L., Fitzgerald, S.P., Ennist, D.L., Elkins, K.L., Ruff, M.R. and Pert, C.B. Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide. Nature 335: 639-642, 1988.

207. Pert, C.B., Ruff, M.R. and Hill, J.M. AIDS as a neuropeptide disorder: Peptide T, VIP, and the HIV receptor. Psychopharmacology Bulletin 24: 315-319, 1988.

208. Smith, C.C., Hallberg, P.L., Sternberg, E.M., Martin, B.M., Pert, C.B. and Ruff, M.R. Tritiated D-ala1 peptide T binding: A pharmacologic basis for the design of drugs which inhibit HIV receptor. Drug Dev. Res. 15: 371-379, 1988.

209. Brenneman, D.E., Buzy, J.M., Ruff, M.R. and Pert, C.B. Peptide T prevents gp120 induced neuronal cell death in vitro: Relevance to AIDS dementia. Drug Dev. Res. 15: 361-369, 1988.

210. Farrar, W.L., Kilian, P.L., Ruff, M.R., Hill, J.M., Pert, C.B. Characterization of IL-1 receptors in brain. Adv. Bioch. Psychopharmacol. 44: 35-44, 1988.

211. Bridge, T.P., Heseltine, P.N.R., Parker, E.S., Eaton, E., Ingraham, L.J., Gill, M., Ruff, M.R., Pert, C.B., and Goodwin, F.K. Improvements in AIDS patients on peptide T. The Lancet July 22,p 226-227, l989

212. Hill, J.M. and Pert, C.B. Neurochemical basis of emotional behavior. In: Handbook of Neuropsychology Vol. 3, Boller, F. and Grafman, J. (Eds.). Elsevier, Amsterdam, 1989, pp. 305-314.

213. Mark, G.E., Pfeifer, A., Mann, D.L., Harris, C.C., and Pert, C.B. Raf protooncogene expression in neural and immune tissues. Adv. Biochem. Psychopharm. 44: 45-55, 1988.

214. Zipser, B., Ruff, M.R., O’Neill, J.B., Smith, C.C., Higgins, W.J. and Pert, C.B. The opiate receptor: a single 110 Kd recognition molecule appears to be conserved in Tetrahymena, leech and rat. Brain Res. 463: 296-304, 1988

215. Wiedermann, C.J., Adamson, I.Y., Pert, C.B., and Bowden, D.H. Enhanced secretion of bombesin by alveloar macrophages exposed to silica. J. Leukoc. Biol. 43: 99-103, 1988.

216. Lesniak, M.A., Hill, J.M., Kiess, W., Rojeski, M., Pert, C.B. and Roth, J. Receptors for insulin-like growth factors I and II: Autoradiographic localization in rat brain and comparison to receptors for insulin. Endocrinology 123: 2089-2099, 1988.

217. Ostrowski, N.L., Pert, C.B. and Pert, A. Visualization of opiate receptors in vivo. In: Receptor Localization: Ligand Autoradiography, Leslie, F. and Altor, T. (Eds.). Alan R. Liss, New York, 1988, pp. 129-161.

218. Wiedermann, C.J., Ruff, M.R., and Pert, C.B. Bombesin-like peptides: neuropeptides with mitogenic activity. Brain Behav. Immun. 2: 301-310, 1988.

219. Wiedermann, C.J., Jelesof, N.J., Pert, C.B., Hill, J.M. and Braunsteiner, H. Neuromodulation by polypeptide growth factors: Preliminary results on the distribution of epidermal growth factor receptors in adult brain. Wien Clin Wochenschr 100: 760-763, 1988.

220. Laing, P., Knight, J.G., Hill, J.M., Harris, A.G., Oxford, J.S., Webster, R.G., Markwell, M.A.K., Paul, S.M. and Pert, C.B. Influenza viruses induce autoantibodies to a brain-specific 37-kDa protein in rabbit. Proc. Natl. Acad. Sci. USA 86: 1998-2002, 1989.

221. Pert, C.B., Hill, J.M., Zipser, B. Neurochemical basis of emotional behavior. In: Handbook of Neuropsychology, v3 F. Boller & J. Grafman (eds). Elsevier Amsterdam, 305-314, 1989.

222. Marcusson, J.A., Lazega, D., Pert, C.B., Ruff, M.R., Sundquist, K.G. and Wetterberg, L. Peptide T and psoriasis. Acta Derm. Venereol. (Stockh), Suppl. 146: 117-121, 1989.

223. Buzy, J.M., Brenneman, D.E., Siegal, F.P., Ruff, M.R. and Pert, C.B. Gp120-like neuronal killing in vitro by the cerebrospinal fluid from a cognitively impaired patient with acquired immunodeficiency syndrome. The Am. J. Med. 87: 361-362, 1989.

224. Jaffe, H., O’Neill, J.B., Hallberg, P.L., Kingan, T., Barbour, G., Lawson, M., Kwart, L.D., Ruff, M.R., Pert, C.B. and Rao, K.R. Isolation and identification of a peptide from rat brain which inhibits [3H]TCP binding. Int. J. Biochem. 22: 239-245, 1990.

225. O’Neill, J.B., Jaffe, H., Hallberg, P.L., Buzy, J.M., Kingan, T., Barbour, G., Lawson, M., Kwart, L.D., Ruff, M.R., Pert, C.B. and Rao, K.R. Identification of a domain in cytochrome C that displaces [3H]TCP binding from rat brain membrane receptors: Synthesis of ß-neuroprotectin. Int. J. Biochem. 22: 335-339, 1990.

226. Fagarasan, M.O., Hallberg, P.L., Russell, D.H., Zorn, N.E., Ruff, M.R., and Pert, C.B. HIV envelope protein (gp120) activates rat spenocyte and human monocyte nuclear protein kinase C: A possible mechanism for immunodeficiency in HIV infection. Int. J. Neurosci., in press.

227. Bridge, T.P., Mayer, K.H., Linde, L., Eaton, E., Parker, E.S., Ingraham, L., Ollo, C., Ruff M.R., Pert, C.B., and Goodwin, F.G. Neuropsychologic results of controlled trial of peptide T in HIV-1. Psychopharma. Bull., in press.

228. Sacerdote, P., Wiedermann, C.J., Wahl, L.M., Pert, C.B. and Ruff, M.R. Visualization and characterization of cholecystokinin receptors on a subset of human monocytes and in rat spleen. Peptides 12: 167-176, 1991.

229. Ruff, M.R., Smith, C., Kingan, T., Jaffe, H., Heseltine, P., Gill, M.A., Mayer, K., Pert, C.B., and Bridge, T.P. Pharmacokinetics of peptide T in patients with acquired immunodeficiency syndrome (AIDS). Prog. Neuro. Psychopharm. 15: 791-801, 1991.

230. Buzy, J.M., Ruff, M.R., Brenneman, D.E., Salazar, A., Martin, A., and Pert, C.B. Identification of gp120-like pathogenic activity in the cerebrospinal fluid of HIV-infected patients. Brain Res., 598: 10-18, 1992.

231. Mayer, K., Bridge, T.P., Moon, M., Huyett, J., Linde, R., Roffman, M., Ruff, M.R., and Pert, C.B.. A phase I study of intranasal peptide T for the treatment of HIV-infected patients: Clinical and laboratory results. (submitted).

232. O’Neill, J.B., Jaffe, H., Hill, J.M., Buzy, J., Kingan, T., Barbour, G.M., Kwart, L., Bowen, W., Ruff, M.R., Pert, C.B. Neuroprotectin, a peptide isolated from brain which potently inhibits NMDA-induced neurotoxicity both in vitro and in vivo. (submitted)

233. Ruff, MR., Pert, CB., Bradley, B., Loveless, M., Darmanandra,S. and Phillips, TM. (1995) An analysis of fifteeen cytokine changes in adult HIV patients receiving peptide T for seven weeks. AIDS Res Hu Retro Viruses 11 S1: abstr #393

234. Villemagne, V.L. Phillips, R.L:., Liu, X., Gilson, S.F., Dannals, R.F., Wong, D.F., Harris, P., Ruff, M.R., Pert, C.B., Bridge, P., and London, E. Peptide T increases cerebral glucose metabolism in an impaired HIV symptomatic patient: A PET study. J Nucl Med. 1996 Jul;37(7):1177-80.

235. Socci, D.J., Pert, C.B., Ruff, M.R., and Arendash, G.W. The VIP analog Peptide T prevents NBM lesion-induced cortical atrophy in aged rats. Peptides (1996)17:831-837

236. Pert CB, Dreher HE, Ruff MR The psychosomatic network: foundations of mind-body medicine. Altern Ther Health Med 4:30-41, 1998

237. Mulroney SE, McDonnell KJ, Pert CB, Ruff MR, Resch Z, Samson WK, Lumpkin MD. HIV gp120 inhibits the somatotropic axis: a possibleGH-releasing hormone receptor mechanism for thepathogenesis of AIDS wasting. Proc Natl Acad Sci U S A 95(4):1927-1932, 1998

238. Kim,J., Ruff, M., Karwatowska. E., Hunt , L, Ji,H., Pert, C., and Zukowska-Grojec,Z. HIV envelope protein gp120 induces neuropeptide Y receptor-mediated proliferation of vascular smooth muscle cells: relevance to AIDS cardiovascular pathogenesis. (in press Reg. Peptides)

239. Raychaudhuri, SP., Jiang,WY., Farber, EM., Schall, TJ., Ruff, MR., Pert, CB. Upregulation of RANTES in psoriatic keratinocytes: A possible pathogenic mechanism in psoriasis. Acta Derm. Vener. (in press)

240. Brenneman, DE., Hauser, JM, Spong,CY., Phillips, TM., Pert, CB., and Ruff, MR. VIP and D-Ala1-Peptide T-amide release chemokines which prevent HIV-1 gp120 induced neuronal death. Brain Res. 838:27.

241. Laura S. Redwine, Janice D. Rone, Candace B. Pert, Robin Nixon, Matthew Vance, Bryan Sandler, Michael D. Lumpkin, and, Michael R. Ruff. GP120(V2)-Derived Peptide T Blocks GP120/CCR5 Chemokine Receptor Mediated Chemotaxis. Clinical Immunology. 93:124.

242. Dieter, D.J., Ruff, M., Hicks, J., Pert, C.B. Structure-Function Analysis of Systematic Glycosylated Derivatives of the HIV Therapeutic Peptide T. (in review)

243. Michael R. Ruff, Ph.D, Loyda M. Melendez-Guerrero, Ph.D., Quan-en Yang, M.D., Wen-Zhe Ho, M.D., Judy Mikovits, Ph.D., Candace B. Pert, Ph.D and Francis Ruscetti, Ph.D. Peptide T Inhibits HIV-1 Infection Mediated by the Chemokine Receptor -5 (CCR5). Antiviral Res. 52:63-75 (2001)

244. Barbey-Morel C, McDonnell K, Pert C, Adams M, Farrand D, Ruff M, Lumpkin M. A Peptide T Bolus Normalizes Growth Hormone Secretion Pattern in Two Children with AIDS Peptides 6538:1-3 (2002)

245. Maria Polianova, C.B. Pert, Francis W. Ruscetti, and M.R. Ruff. Peptide T Inhibits HIV-1 Envelope Protein (Gp120) Binding To Chemokine Receptor-5. in review.

246. Michael R. Ruff, M. Polianova, Yang, Q,Francis W. Ruscetti , and C.B. Pert. Update On D-Ala-Peptide T-Amide (DAPTA), A Viral Entry Inhibitor Which Blocks R5 Chemokine Receptors. Curr HIV Res 1:51-67 (2003)

247. Maria T. Polianova, Gifford Leoung, Scott Strang, Candace B. Pert , Francis W. Ruscetti, Michael R. Ruff1. Antiviral and immunological benefits in HIV patients receiving peptide T. Peptides 24:1093-1098 (2003)

248. Maria Polianova, C.B. Pert, ,Francis W. Ruscetti, and M.R. Ruff. Peptide T (DAPTA) Chemokine receptor-5 (CCR5) is a receptor for the HIV entry inhibitor peptide T (DAPTA). Antiviral Res. 2005 Aug;67(2):83-92..

249. Susanna Rosi, Candace B. Pert, Michael R. Ruff, Kristin McGann-Gramling and Gary L. Wenk. CCR5 Chemokine Receptor Antagonist DAPTA Reduces Microglia and Astrocyte activation within the Hippocampus in a Neuroinflammatory Rat Model of Alzheimer’s Disease Neuroscience. 2005;134(2):671-6.

250. Padi, SS, et al. (2012), ‘Attenuation of rodent neuropathic pain by an orally active peptide, RAP-103, which potently blocks CCR2- and CCR5-mediated monocyte chemotaxis and inflammation.’, Pain, 153 (1), 95-106.

251. Dieter, D.J., Ruff, M., Hicks, J., Pert, C.B. Structure-Function Analysis of Systematic Glycosylated Derivatives of the HIV Therapeutic Peptide T. (in rewiew)

252. Maria Polianova, C.B. Pert, ,Francis W. Ruscetti, and M.R. Ruff. Production of potent, broadly neutralizing vaccine antibodies for HIV by immunization with a binding-site derived small peptide. (in review).